Difference between revisions of "YPL123C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006044 YPL123C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006044 YPL123C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RNY1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RNY1 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YPL123C
Gene name RNY1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:318945..317641
Primary SGDID S000006044


Description of YPL123C: Vacuolar RNase of the T(2) family, relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity[1][2]




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References

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  1. MacIntosh GC, et al. (2001) Characterization of Rny1, the Saccharomyces cerevisiae member of the T2 RNase family of RNases: unexpected functions for ancient enzymes? Proc Natl Acad Sci U S A 98(3):1018-23 SGD PMID 11158587
  2. Thompson DM and Parker R (2009) The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae. J Cell Biol 185(1):43-50 SGD PMID 19332891

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