YPL123C
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| Systematic name | YPL123C |
| Gene name | RNY1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:318945..317641 |
| Primary SGDID | S000006044 |
Description of YPL123C: Vacuolar RNase of the T(2) family, relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity[1][2]
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References
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- ↑ MacIntosh GC, et al. (2001) Characterization of Rny1, the Saccharomyces cerevisiae member of the T2 RNase family of RNases: unexpected functions for ancient enzymes? Proc Natl Acad Sci U S A 98(3):1018-23 SGD PMID 11158587
- ↑ Thompson DM and Parker R (2009) The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae. J Cell Biol 185(1):43-50 SGD PMID 19332891
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