Difference between revisions of "YDL154W"
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| − | '''Description of YDL154W:''' Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans<ref name='S000075349'>Bawa S and Xiao W (2003) A single amino acid substitution in MSH5 results in DNA alkylation tolerance. Gene 315 | + | '''Description of YDL154W:''' Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans<ref name='S000075349'>Bawa S and Xiao W (2003) A single amino acid substitution in MSH5 results in DNA alkylation tolerance. Gene 315:177-82 {{SGDpaper|S000075349}} PMID 14557077</ref><ref name='S000049715'>Pochart P, et al. (1997) Conserved properties between functionally distinct MutS homologs in yeast. J Biol Chem 272(48):30345-9 {{SGDpaper|S000049715}} PMID 9374523</ref><ref name='S000042564'>Winand NJ, et al. (1998) Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene. Genomics 53(1):69-80 |
{{SGDpaper|S000042564}} PMID 9787078</ref> | {{SGDpaper|S000042564}} PMID 9787078</ref> | ||
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Revision as of 14:05, 18 July 2007
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| Systematic name | YDL154W |
| Gene name | MSH5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:178335..181040 |
| Primary SGDID | S000002313 |
Description of YDL154W: Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans[1][2][3]
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References
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- ↑ Bawa S and Xiao W (2003) A single amino acid substitution in MSH5 results in DNA alkylation tolerance. Gene 315:177-82 SGD PMID 14557077
- ↑ Pochart P, et al. (1997) Conserved properties between functionally distinct MutS homologs in yeast. J Biol Chem 272(48):30345-9 SGD PMID 9374523
- ↑ Winand NJ, et al. (1998) Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene. Genomics 53(1):69-80 SGD PMID 9787078
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