Difference between revisions of "YKL004W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001487 YKL004W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AUR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AUR1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XI:435223..436428 | |nowrap| Chr XI:435223..436428 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001487 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YKL004W:''' Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance<ref name='S000054617'>Heidler SA and Radding JA (1995) The AUR1 gene in Saccharomyces cerevisiae encodes dominant resistance to the antifungal agent aureobasidin A (LY295337). Antimicrob Agents Chemother 39(12):2765-9 {{SGDpaper|S000054617}} PMID 8593016</ref><ref name='S000053853'>Nagiec MM, et al. (1997) Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J Biol Chem 272(15):9809-17 |
{{SGDpaper|S000053853}} PMID 9092515</ref> | {{SGDpaper|S000053853}} PMID 9092515</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YKL004W |
| Gene name | AUR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:435223..436428 |
| Primary SGDID | S000001487 |
Description of YKL004W: Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance[1][2]
</protect>
Contents
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References
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- ↑ Heidler SA and Radding JA (1995) The AUR1 gene in Saccharomyces cerevisiae encodes dominant resistance to the antifungal agent aureobasidin A (LY295337). Antimicrob Agents Chemother 39(12):2765-9 SGD PMID 8593016
- ↑ Nagiec MM, et al. (1997) Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J Biol Chem 272(15):9809-17 SGD PMID 9092515
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