Difference between revisions of "YIL146C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YIL146C YIL146C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001408 YIL146C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ECM37 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG32 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''ECM37''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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|nowrap| Chr IX:75773..74184
 
|nowrap| Chr IX:75773..74184
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001408
 
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'''Description of {{PAGENAME}}:''' Non-essential protein of unknown function<ref name='S000073348'>SGD (2003) Information without a citation in SGD  ()
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'''Description of YIL146C:''' Mitochondrial outer membrane protein required to initiate mitophagy; recruits the autophagy adaptor protein Atg11p and the ubiquitin-like protein Atg8p to the mitochondrial surface to initiate mitophagy, the selective vacuolar degradation of mitochondria in response to starvation; can promote pexophagy when placed ectopically in the peroxisomal membrane<ref name='S000131016'>Kanki T, et al. (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17(1):98-109 {{SGDpaper|S000131016}} PMID 19619495</ref><ref name='S000148322'>Kondo-Okamoto N, et al. (2012) Autophagy-related protein 32 acts as an autophagic degron and directly initiates mitophagy. J Biol Chem () {{SGDpaper|S000148322}} PMID 22308029</ref><ref name='S000131021'>Okamoto K, et al. (2009) Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1):87-97
  {{SGDpaper|S000073348}} PMID </ref>
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  {{SGDpaper|S000131021}} PMID 19619494</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 14:05, 24 February 2012

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Systematic name YIL146C
Gene name ATG32
Aliases ECM37
Feature type ORF, Verified
Coordinates Chr IX:75773..74184
Primary SGDID S000001408


Description of YIL146C: Mitochondrial outer membrane protein required to initiate mitophagy; recruits the autophagy adaptor protein Atg11p and the ubiquitin-like protein Atg8p to the mitochondrial surface to initiate mitophagy, the selective vacuolar degradation of mitochondria in response to starvation; can promote pexophagy when placed ectopically in the peroxisomal membrane[1][2][3]




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Community Commentary

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References

See Help:References on how to add references

  1. Kanki T, et al. (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17(1):98-109 SGD PMID 19619495
  2. Kondo-Okamoto N, et al. (2012) Autophagy-related protein 32 acts as an autophagic degron and directly initiates mitophagy. J Biol Chem () SGD PMID 22308029
  3. Okamoto K, et al. (2009) Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1):87-97 SGD PMID 19619494

See Help:Categories on how to add the wiki page for this gene to a Category </protect>