Difference between revisions of "YIL146C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001408 YIL146C] |
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ATG32 '' |
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''ECM37'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IX:75773..74184 | |nowrap| Chr IX:75773..74184 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001408 | ||
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| − | '''Description of {{ | + | '''Description of YIL146C:''' Mitochondrial outer membrane protein required to initiate mitophagy; recruits the autophagy adaptor protein Atg11p and the ubiquitin-like protein Atg8p to the mitochondrial surface to initiate mitophagy, the selective vacuolar degradation of mitochondria in response to starvation; can promote pexophagy when placed ectopically in the peroxisomal membrane<ref name='S000131016'>Kanki T, et al. (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17(1):98-109 {{SGDpaper|S000131016}} PMID 19619495</ref><ref name='S000148322'>Kondo-Okamoto N, et al. (2012) Autophagy-related protein 32 acts as an autophagic degron and directly initiates mitophagy. J Biol Chem () {{SGDpaper|S000148322}} PMID 22308029</ref><ref name='S000131021'>Okamoto K, et al. (2009) Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1):87-97 |
| − | {{SGDpaper| | + | {{SGDpaper|S000131021}} PMID 19619494</ref> |
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Latest revision as of 14:05, 24 February 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YIL146C |
| Gene name | ATG32 |
| Aliases | ECM37 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:75773..74184 |
| Primary SGDID | S000001408 |
Description of YIL146C: Mitochondrial outer membrane protein required to initiate mitophagy; recruits the autophagy adaptor protein Atg11p and the ubiquitin-like protein Atg8p to the mitochondrial surface to initiate mitophagy, the selective vacuolar degradation of mitochondria in response to starvation; can promote pexophagy when placed ectopically in the peroxisomal membrane[1][2][3]
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References
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- ↑ Kanki T, et al. (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17(1):98-109 SGD PMID 19619495
- ↑ Kondo-Okamoto N, et al. (2012) Autophagy-related protein 32 acts as an autophagic degron and directly initiates mitophagy. J Biol Chem () SGD PMID 22308029
- ↑ Okamoto K, et al. (2009) Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1):87-97 SGD PMID 19619494
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