Difference between revisions of "YIL146C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
 
Line 18: Line 18:
 
|}
 
|}
 
<br>
 
<br>
'''Description of YIL146C:''' Mitochondrial-anchored transmembrane receptor that interacts with the autophagy adaptor protein, Atg11p, and is essential for mitophagy, the selective vacuolar degradation of mitochondria in response to starvation<ref name='S000131016'>Kanki T, et al. (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17(1):98-109 {{SGDpaper|S000131016}} PMID 19619495</ref><ref name='S000131021'>Okamoto K, et al. (2009) Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1):87-97
+
'''Description of YIL146C:''' Mitochondrial outer membrane protein required to initiate mitophagy; recruits the autophagy adaptor protein Atg11p and the ubiquitin-like protein Atg8p to the mitochondrial surface to initiate mitophagy, the selective vacuolar degradation of mitochondria in response to starvation; can promote pexophagy when placed ectopically in the peroxisomal membrane<ref name='S000131016'>Kanki T, et al. (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17(1):98-109 {{SGDpaper|S000131016}} PMID 19619495</ref><ref name='S000148322'>Kondo-Okamoto N, et al. (2012) Autophagy-related protein 32 acts as an autophagic degron and directly initiates mitophagy. J Biol Chem () {{SGDpaper|S000148322}} PMID 22308029</ref><ref name='S000131021'>Okamoto K, et al. (2009) Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1):87-97
 
  {{SGDpaper|S000131021}} PMID 19619494</ref>
 
  {{SGDpaper|S000131021}} PMID 19619494</ref>
 
<br>
 
<br>

Latest revision as of 14:05, 24 February 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YIL146C
Gene name ATG32
Aliases ECM37
Feature type ORF, Verified
Coordinates Chr IX:75773..74184
Primary SGDID S000001408


Description of YIL146C: Mitochondrial outer membrane protein required to initiate mitophagy; recruits the autophagy adaptor protein Atg11p and the ubiquitin-like protein Atg8p to the mitochondrial surface to initiate mitophagy, the selective vacuolar degradation of mitochondria in response to starvation; can promote pexophagy when placed ectopically in the peroxisomal membrane[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Kanki T, et al. (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17(1):98-109 SGD PMID 19619495
  2. Kondo-Okamoto N, et al. (2012) Autophagy-related protein 32 acts as an autophagic degron and directly initiates mitophagy. J Biol Chem () SGD PMID 22308029
  3. Okamoto K, et al. (2009) Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1):87-97 SGD PMID 19619494

See Help:Categories on how to add the wiki page for this gene to a Category </protect>