Difference between revisions of "YGR099W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003331 YGR099W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TEL2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TEL2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:687899..689965 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003331 |
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| − | '''Description of | + | '''Description of YGR099W:''' Subunit of the ASTRA complex, involved in chromatin remodeling; subunit of the telomere cap complex DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect; involved in the stability or biogenesis of PIKKs such as TORC1<ref name='S000039507'>Kota RS and Runge KW (1998) The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA. Nucleic Acids Res 26(6):1528-35 {{SGDpaper|S000039507}} PMID 9490802</ref><ref name='S000052011'>Kota RS and Runge KW (1999) Tel2p, a regulator of yeast telomeric length in vivo, binds to single-stranded telomeric DNA in vitro. Chromosoma 108(5):278-90 {{SGDpaper|S000052011}} PMID 10525964</ref><ref name='S000055772'>Runge KW and Zakian VA (1996) TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 16(6):3094-105 {{SGDpaper|S000055772}} PMID 8649421</ref><ref name='S000128493'>Shevchenko A, et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9(11):R167 {{SGDpaper|S000128493}} PMID 19040720</ref><ref name='S000145356'>Stirling PC, et al. (2011) The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components. PLoS Genet 7(4):e1002057 |
| − | {{SGDpaper| | + | {{SGDpaper|S000145356}} PMID 21552543</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 14:05, 16 February 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR099W |
| Gene name | TEL2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:687899..689965 |
| Primary SGDID | S000003331 |
Description of YGR099W: Subunit of the ASTRA complex, involved in chromatin remodeling; subunit of the telomere cap complex DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect; involved in the stability or biogenesis of PIKKs such as TORC1[1][2][3][4][5]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Kota RS and Runge KW (1998) The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA. Nucleic Acids Res 26(6):1528-35 SGD PMID 9490802
- ↑ Kota RS and Runge KW (1999) Tel2p, a regulator of yeast telomeric length in vivo, binds to single-stranded telomeric DNA in vitro. Chromosoma 108(5):278-90 SGD PMID 10525964
- ↑ Runge KW and Zakian VA (1996) TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 16(6):3094-105 SGD PMID 8649421
- ↑ Shevchenko A, et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9(11):R167 SGD PMID 19040720
- ↑ Stirling PC, et al. (2011) The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components. PLoS Genet 7(4):e1002057 SGD PMID 21552543
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