YGR099W
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| Systematic name | YGR099W |
| Gene name | TEL2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:687899..689965 |
| Primary SGDID | S000003331 |
Description of YGR099W: Subunit of the ASTRA complex, involved in chromatin remodeling; subunit of the telomere cap complex DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect; involved in the stability or biogenesis of PIKKs such as TORC1[1][2][3][4][5]
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References
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- ↑ Kota RS and Runge KW (1998) The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA. Nucleic Acids Res 26(6):1528-35 SGD PMID 9490802
- ↑ Kota RS and Runge KW (1999) Tel2p, a regulator of yeast telomeric length in vivo, binds to single-stranded telomeric DNA in vitro. Chromosoma 108(5):278-90 SGD PMID 10525964
- ↑ Runge KW and Zakian VA (1996) TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 16(6):3094-105 SGD PMID 8649421
- ↑ Shevchenko A, et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9(11):R167 SGD PMID 19040720
- ↑ Stirling PC, et al. (2011) The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components. PLoS Genet 7(4):e1002057 SGD PMID 21552543
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