Difference between revisions of "YPR067W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006271 YPR067W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ISA2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ISA2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:682220..682777 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006271 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006271 | ||
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| − | '''Description of YPR067W:''' Protein required for maturation of mitochondrial and | + | '''Description of YPR067W:''' Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa1p and possibly Iba57p; localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations<ref name='S000043306'>Jensen LT and Culotta VC (2000) Role of Saccharomyces cerevisiae ISA1 and ISA2 in iron homeostasis. Mol Cell Biol 20(11):3918-27 {{SGDpaper|S000043306}} PMID 10805735</ref><ref name='S000147072'>Muhlenhoff U, et al. (2011) SPECIALIZED FUNCTION OF YEAST ISA1 AND ISA2 IN THE MATURATION OF MITOCHONDRIAL [4FE-4S] PROTEINS. J Biol Chem () {{SGDpaper|S000147072}} PMID 21987576</ref><ref name='S000048128'>Pelzer W, et al. (2000) Mitochondrial Isa2p plays a crucial role in the maturation of cellular iron-sulfur proteins. FEBS Lett 476(3):134-9 {{SGDpaper|S000048128}} PMID 10913600</ref><ref name='S000071410'>Rodriguez-Manzaneque MT, et al. (2002) Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol Biol Cell 13(4):1109-21 |
{{SGDpaper|S000071410}} PMID 11950925</ref> | {{SGDpaper|S000071410}} PMID 11950925</ref> | ||
<br> | <br> | ||
Latest revision as of 07:45, 23 January 2012
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| Systematic name | YPR067W |
| Gene name | ISA2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:682220..682777 |
| Primary SGDID | S000006271 |
Description of YPR067W: Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa1p and possibly Iba57p; localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations[1][2][3][4]
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References
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- ↑ Jensen LT and Culotta VC (2000) Role of Saccharomyces cerevisiae ISA1 and ISA2 in iron homeostasis. Mol Cell Biol 20(11):3918-27 SGD PMID 10805735
- ↑ Muhlenhoff U, et al. (2011) SPECIALIZED FUNCTION OF YEAST ISA1 AND ISA2 IN THE MATURATION OF MITOCHONDRIAL [4FE-4S] PROTEINS. J Biol Chem () SGD PMID 21987576
- ↑ Pelzer W, et al. (2000) Mitochondrial Isa2p plays a crucial role in the maturation of cellular iron-sulfur proteins. FEBS Lett 476(3):134-9 SGD PMID 10913600
- ↑ Rodriguez-Manzaneque MT, et al. (2002) Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol Biol Cell 13(4):1109-21 SGD PMID 11950925
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