YPR067W
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| Systematic name | YPR067W |
| Gene name | ISA2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:682220..682777 |
| Primary SGDID | S000006271 |
Description of YPR067W: Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa1p and possibly Iba57p; localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations[1][2][3][4]
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References
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- ↑ Jensen LT and Culotta VC (2000) Role of Saccharomyces cerevisiae ISA1 and ISA2 in iron homeostasis. Mol Cell Biol 20(11):3918-27 SGD PMID 10805735
- ↑ Muhlenhoff U, et al. (2011) SPECIALIZED FUNCTION OF YEAST ISA1 AND ISA2 IN THE MATURATION OF MITOCHONDRIAL [4FE-4S] PROTEINS. J Biol Chem () SGD PMID 21987576
- ↑ Pelzer W, et al. (2000) Mitochondrial Isa2p plays a crucial role in the maturation of cellular iron-sulfur proteins. FEBS Lett 476(3):134-9 SGD PMID 10913600
- ↑ Rodriguez-Manzaneque MT, et al. (2002) Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol Biol Cell 13(4):1109-21 SGD PMID 11950925
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