Difference between revisions of "YOL071W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005432 YOL071W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EMI5 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EMI5 '' | ||
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| − | '''Description of YOL071W:''' | + | '''Description of YOL071W:''' Subunit of succinate dehydrogenase, which couples succinate oxidation to ubiquinone reduction; required for FAD cofactor attachment to Sdh1p; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma)<ref name='S000073751'>Deutschbauer AM, et al. (2002) Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 99(24):15530-5 {{SGDpaper|S000073751}} PMID 12432101</ref><ref name='S000072583'>Enyenihi AH and Saunders WS (2003) Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae. Genetics 163(1):47-54 {{SGDpaper|S000072583}} PMID 12586695</ref><ref name='S000131003'>Hao HX, et al. (2009) SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science 325(5944):1139-42 {{SGDpaper|S000131003}} PMID 19628817</ref><ref name='S000080581'>Romano JD and Kolter R (2005) Pseudomonas-Saccharomyces interactions: influence of fungal metabolism on bacterial physiology and survival. J Bacteriol 187(3):940-8 |
| − | {{SGDpaper| | + | {{SGDpaper|S000080581}} PMID 15659672</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YOL071W |
| Gene name | EMI5 |
| Aliases | SDH5 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:196507..196995 |
| Primary SGDID | S000005432 |
Description of YOL071W: Subunit of succinate dehydrogenase, which couples succinate oxidation to ubiquinone reduction; required for FAD cofactor attachment to Sdh1p; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma)[1][2][3][4]
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References
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- ↑ Deutschbauer AM, et al. (2002) Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 99(24):15530-5 SGD PMID 12432101
- ↑ Enyenihi AH and Saunders WS (2003) Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae. Genetics 163(1):47-54 SGD PMID 12586695
- ↑ Hao HX, et al. (2009) SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science 325(5944):1139-42 SGD PMID 19628817
- ↑ Romano JD and Kolter R (2005) Pseudomonas-Saccharomyces interactions: influence of fungal metabolism on bacterial physiology and survival. J Bacteriol 187(3):940-8 SGD PMID 15659672
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