Difference between revisions of "YNL128W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005072 YNL128W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005072 YNL128W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TEP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TEP1 ''
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'''Description of YNL128W:''' Homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 that has lipid phosphatase activity and is linked to the phosphatidylinositol signaling pathway; plays a role in normal sporulation<ref name='S000059409'>Heymont J, et al. (2000) TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation. Proc Natl Acad Sci U S A 97(23):12672-7 {{SGDpaper|S000059409}} PMID 11070083</ref><ref name='S000079695'>Huang J, et al. (2004) Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips. Proc Natl Acad Sci U S A 101(47):16594-9
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'''Description of YNL128W:''' PTEN homolog with no demonstrated inositol lipid phosphatase activity; plays a role in normal sporulation; homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and fission yeast ptn1<ref name='S000059409'>Heymont J, et al. (2000) TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation. Proc Natl Acad Sci U S A 97(23):12672-7 {{SGDpaper|S000059409}} PMID 11070083</ref><ref name='S000147691'>Maehama T, et al. (2001) PTEN and myotubularin: novel phosphoinositide phosphatases. Annu Rev Biochem 70():247-79 {{SGDpaper|S000147691}} PMID 11395408</ref><ref name='S000076675'>Mitra P, et al. (2004) A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast. J Cell Biol 166(2):205-11 {{SGDpaper|S000076675}} PMID 15249580</ref><ref name='S000081790'>Rodriguez-Escudero I, et al. (2005) Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast. Biochem J 390(Pt 2):613-23
  {{SGDpaper|S000079695}} PMID 15539461</ref>
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  {{SGDpaper|S000081790}} PMID 15913452</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YNL128W
Gene name TEP1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:382359..383663
Primary SGDID S000005072


Description of YNL128W: PTEN homolog with no demonstrated inositol lipid phosphatase activity; plays a role in normal sporulation; homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and fission yeast ptn1[1][2][3][4]




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References

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  1. Heymont J, et al. (2000) TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation. Proc Natl Acad Sci U S A 97(23):12672-7 SGD PMID 11070083
  2. Maehama T, et al. (2001) PTEN and myotubularin: novel phosphoinositide phosphatases. Annu Rev Biochem 70():247-79 SGD PMID 11395408
  3. Mitra P, et al. (2004) A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast. J Cell Biol 166(2):205-11 SGD PMID 15249580
  4. Rodriguez-Escudero I, et al. (2005) Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast. Biochem J 390(Pt 2):613-23 SGD PMID 15913452

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