Difference between revisions of "YLR437C"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR437C YLR437C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004429 YLR437C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DIF1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Uncharacterized[[Category:ORF]][[Category:ORF, Uncharacterized]]
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:1012020..1011619
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|nowrap| Chr XII:1012023..1011622
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004429
 
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'''Description of {{PAGENAME}}:''' Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm<ref name='S000069459'>Kumar A, et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19
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'''Description of YLR437C:''' Protein that regulates the nuclear localization of ribonucleotide reductase Rnr2p and Rnr4p subunits; phosphorylated by Dun1p in response to DNA damage and degraded; N-terminal half has similarity to S. pombe Spd1 protein<ref name='S000128018'>Lee YD, et al. (2008) Dif1 is a DNA-damage-regulated facilitator of nuclear import for ribonucleotide reductase. Mol Cell 32(1):70-80 {{SGDpaper|S000128018}} PMID 18851834</ref><ref name='S000127965'>Wu X and Huang M (2008) Dif1 controls subcellular localization of ribonucleotide reductase by mediating nuclear import of the r2 subunit. Mol Cell Biol 28(23):7156-67
  {{SGDpaper|S000069459}} PMID 11914276</ref>
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  {{SGDpaper|S000127965}} PMID 18838542</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YLR437C
Gene name DIF1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:1012023..1011622
Primary SGDID S000004429


Description of YLR437C: Protein that regulates the nuclear localization of ribonucleotide reductase Rnr2p and Rnr4p subunits; phosphorylated by Dun1p in response to DNA damage and degraded; N-terminal half has similarity to S. pombe Spd1 protein[1][2]




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References

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  1. Lee YD, et al. (2008) Dif1 is a DNA-damage-regulated facilitator of nuclear import for ribonucleotide reductase. Mol Cell 32(1):70-80 SGD PMID 18851834
  2. Wu X and Huang M (2008) Dif1 controls subcellular localization of ribonucleotide reductase by mediating nuclear import of the r2 subunit. Mol Cell Biol 28(23):7156-67 SGD PMID 18838542

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