Difference between revisions of "YGR098C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003330 YGR098C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ESP1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ESP1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:687458..682566 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003330 |
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| − | '''Description of | + | '''Description of YGR098C:''' Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p<ref name='S000054076'>Ciosk R, et al. (1998) An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93(6):1067-76 {{SGDpaper|S000054076}} PMID 9635435</ref><ref name='S000116004'>Queralt E, et al. (2006) Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast. Cell 125(4):719-32 {{SGDpaper|S000116004}} PMID 16713564</ref><ref name='S000062956'>Uhlmann F, et al. (2000) Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell 103(3):375-86 |
| − | {{SGDpaper| | + | {{SGDpaper|S000062956}} PMID 11081625</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR098C |
| Gene name | ESP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:687458..682566 |
| Primary SGDID | S000003330 |
Description of YGR098C: Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p[1][2][3]
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Contents
Community Commentary
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References
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- ↑ Ciosk R, et al. (1998) An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93(6):1067-76 SGD PMID 9635435
- ↑ Queralt E, et al. (2006) Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast. Cell 125(4):719-32 SGD PMID 16713564
- ↑ Uhlmann F, et al. (2000) Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell 103(3):375-86 SGD PMID 11081625
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