Difference between revisions of "YGL246C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003215 YGL246C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAI1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAI1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VII:38780..37617 | |nowrap| Chr VII:38780..37617 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003215 | ||
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| − | '''Description of | + | '''Description of YGL246C:''' Nuclear protein with decapping endonuclease activity targeted toward mRNAs with unmethylated 7-methylguanosine cap structures; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; homologous to human DOM3Z<ref name='S000136242'>Jiao X, et al. (2010) Identification of a quality-control mechanism for mRNA 5'-end capping. Nature 467(7315):608-11 {{SGDpaper|S000136242}} PMID 20802481</ref><ref name='S000072983'>Sydorskyy Y, et al. (2003) Intersection of the Kap123p-mediated nuclear import and ribosome export pathways. Mol Cell Biol 23(6):2042-54 {{SGDpaper|S000072983}} PMID 12612077</ref><ref name='S000043334'>Xue Y, et al. (2000) Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Mol Cell Biol 20(11):4006-15 |
{{SGDpaper|S000043334}} PMID 10805743</ref> | {{SGDpaper|S000043334}} PMID 10805743</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL246C |
| Gene name | RAI1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:38780..37617 |
| Primary SGDID | S000003215 |
Description of YGL246C: Nuclear protein with decapping endonuclease activity targeted toward mRNAs with unmethylated 7-methylguanosine cap structures; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; homologous to human DOM3Z[1][2][3]
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References
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- ↑ Jiao X, et al. (2010) Identification of a quality-control mechanism for mRNA 5'-end capping. Nature 467(7315):608-11 SGD PMID 20802481
- ↑ Sydorskyy Y, et al. (2003) Intersection of the Kap123p-mediated nuclear import and ribosome export pathways. Mol Cell Biol 23(6):2042-54 SGD PMID 12612077
- ↑ Xue Y, et al. (2000) Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Mol Cell Biol 20(11):4006-15 SGD PMID 10805743
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