YGL246C
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| Systematic name | YGL246C |
| Gene name | RAI1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:38780..37617 |
| Primary SGDID | S000003215 |
Description of YGL246C: Nuclear protein with decapping endonuclease activity targeted toward mRNAs with unmethylated 7-methylguanosine cap structures; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; homologous to human DOM3Z[1][2][3]
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References
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- Jump up ↑ Jiao X, et al. (2010) Identification of a quality-control mechanism for mRNA 5'-end capping. Nature 467(7315):608-11 SGD PMID 20802481
- Jump up ↑ Sydorskyy Y, et al. (2003) Intersection of the Kap123p-mediated nuclear import and ribosome export pathways. Mol Cell Biol 23(6):2042-54 SGD PMID 12612077
- Jump up ↑ Xue Y, et al. (2000) Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Mol Cell Biol 20(11):4006-15 SGD PMID 10805743
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