Difference between revisions of "YDR440W"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002848 YDR440W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DOT1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DOT1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr IV: | + | |nowrap| Chr IV:1342493..1344241 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002848 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002848 | ||
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− | '''Description of YDR440W:''' Nucleosomal histone H3-Lys79 methylase, | + | '''Description of YDR440W:''' Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response<ref name='S000082068'>Game JC, et al. (2005) X-ray survival characteristics and genetic analysis for nine Saccharomyces deletion mutants that show altered radiation sensitivity. Genetics 169(1):51-63 {{SGDpaper|S000082068}} PMID 15371366</ref><ref name='S000059155'>San-Segundo PA and Roeder GS (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15 {{SGDpaper|S000059155}} PMID 11029058</ref><ref name='S000086737'>Wysocki R, et al. (2005) Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol 25(19):8430-43 {{SGDpaper|S000086737}} PMID 16166626</ref><ref name='S000071381'>van Leeuwen F, et al. (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109(6):745-56 |
− | {{SGDpaper| | + | {{SGDpaper|S000071381}} PMID 12086673</ref> |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YDR440W |
Gene name | DOT1 |
Aliases | PCH1 |
Feature type | ORF, Verified |
Coordinates | Chr IV:1342493..1344241 |
Primary SGDID | S000002848 |
Description of YDR440W: Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response[1][2][3][4]
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References
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- ↑ Game JC, et al. (2005) X-ray survival characteristics and genetic analysis for nine Saccharomyces deletion mutants that show altered radiation sensitivity. Genetics 169(1):51-63 SGD PMID 15371366
- ↑ San-Segundo PA and Roeder GS (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15 SGD PMID 11029058
- ↑ Wysocki R, et al. (2005) Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol 25(19):8430-43 SGD PMID 16166626
- ↑ van Leeuwen F, et al. (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109(6):745-56 SGD PMID 12086673
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