Difference between revisions of "YDL115C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002273 YDL115C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IWR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IWR1 '' | ||
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| − | '''Description of YDL115C:''' | + | '''Description of YDL115C:''' RNA polymerase II transport factor, conserved from yeast to humans; involved in both basal and regulated transcription from RNA polymerase II (RNAP II) promoters, but not itself a transcription factor; interacts with most of the RNAP II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to K1 killer toxin<ref name='S000145131'>Czeko E, et al. (2011) Iwr1 Directs RNA Polymerase II Nuclear Import. Mol Cell 42(2):261-6 {{SGDpaper|S000145131}} PMID 21504834</ref><ref name='S000114782'>Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 {{SGDpaper|S000114782}} PMID 16554755</ref><ref name='S000072994'>Page N, et al. (2003) A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Genetics 163(3):875-94 {{SGDpaper|S000072994}} PMID 12663529</ref><ref name='S000131208'>Peiro-Chova L and Estruch F (2009) The yeast RNA polymerase II-associated factor Iwr1p is involved in the basal and regulated transcription of specific genes. J Biol Chem 284(42):28958-67 |
{{SGDpaper|S000131208}} PMID 19679657</ref> | {{SGDpaper|S000131208}} PMID 19679657</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YDL115C |
| Gene name | IWR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:255126..253995 |
| Primary SGDID | S000002273 |
Description of YDL115C: RNA polymerase II transport factor, conserved from yeast to humans; involved in both basal and regulated transcription from RNA polymerase II (RNAP II) promoters, but not itself a transcription factor; interacts with most of the RNAP II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to K1 killer toxin[1][2][3][4]
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References
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- ↑ Czeko E, et al. (2011) Iwr1 Directs RNA Polymerase II Nuclear Import. Mol Cell 42(2):261-6 SGD PMID 21504834
- ↑ Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 SGD PMID 16554755
- ↑ Page N, et al. (2003) A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Genetics 163(3):875-94 SGD PMID 12663529
- ↑ Peiro-Chova L and Estruch F (2009) The yeast RNA polymerase II-associated factor Iwr1p is involved in the basal and regulated transcription of specific genes. J Biol Chem 284(42):28958-67 SGD PMID 19679657
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