Difference between revisions of "YGR098C"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:17, 30 January 2007

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Systematic name YGR098C
Gene name ESP1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:687462..682570


Description of YGR098C: Separase with cysteine protease activity (related to caspases) that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibited by Pds1p[1][2]




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Community Commentary

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References

See Help:References on how to add references

  1. Uhlmann F, et al. (2000) Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell 103(3):375-86 SGD PMID 11081625
  2. Ciosk R, et al. (1998) An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93(6):1067-76 SGD PMID 9635435

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