Difference between revisions of "YOR204W"

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'''Description of YOR204W:''' ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility<ref name='S000048410'>Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 {{SGDpaper|S000048410}} PMID 10364207</ref><ref name='S000060379'>Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90 {{SGDpaper|S000060379}} PMID 11069307</ref><ref name='S000080391'>Johnstone O, et al. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277(1):92-101
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'''Description of YOR204W:''' ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility<ref name='S000048410'>Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 {{SGDpaper|S000048410}} PMID 10364207</ref><ref name='S000080391'>Johnstone O, et al. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277(1):92-101 {{SGDpaper|S000080391}} PMID 15572142</ref><ref name='S000060379'>Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90
{{SGDpaper|S000080391}} PMID 15572142</ref>
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{{SGDpaper|S000060379}} PMID 11069307</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YOR204W
Gene name DED1
Aliases SPP81
Feature type ORF, Verified
Coordinates Chr XV:722912..724726
Primary SGDID S000005730


Description of YOR204W: ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility[1][2][3]




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References

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  1. Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 SGD PMID 10364207
  2. Johnstone O, et al. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277(1):92-101 SGD PMID 15572142
  3. Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90 SGD PMID 11069307

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