YOR204W
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Systematic name | YOR204W |
Gene name | DED1 |
Aliases | SPP81 |
Feature type | ORF, Verified |
Coordinates | Chr XV:722911..724725 |
Primary SGDID | S000005730 |
Description of YOR204W: ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility[1][2][3]
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References
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- ↑ Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 SGD PMID 10364207
- ↑ Johnstone O, et al. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277(1):92-101 SGD PMID 15572142
- ↑ Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90 SGD PMID 11069307
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