Difference between revisions of "YNL298W"

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'''Description of YNL298W:''' Cdc42p activated signal transducing kinase of the PAK (p21-activated kinase) family, involved in septin ring assembly and cytokinesis; directly phosphorylates septins Cdc3p and Cdc10p; other yeast PAK family members are Ste20p and Skm1p<ref name='S000055422'>Benton BK, et al. (1997) Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis. Mol Cell Biol 17(9):5067-76 {{SGDpaper|S000055422}} PMID 9271384</ref><ref name='S000057413'>Cvrckova F, et al. (1995) Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. Genes Dev 9(15):1817-30 {{SGDpaper|S000057413}} PMID 7649470</ref><ref name='S000077127'>Versele M and Thorner J (2004) Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J Cell Biol 164(5):701-15 {{SGDpaper|S000077127}} PMID 14993234</ref><ref name='S000074263'>Caviston JP, et al. (2003) The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast. Mol Biol Cell 14(10):4051-66
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'''Description of YNL298W:''' Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, which also includes Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, and cytokinesis; phosphorylates septins Cdc3p and Cdc10p<ref name='S000055422'>Benton BK, et al. (1997) Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis. Mol Cell Biol 17(9):5067-76 {{SGDpaper|S000055422}} PMID 9271384</ref><ref name='S000057413'>Cvrckova F, et al. (1995) Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. Genes Dev 9(15):1817-30 {{SGDpaper|S000057413}} PMID 7649470</ref><ref name='S000077127'>Versele M and Thorner J (2004) Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J Cell Biol 164(5):701-15 {{SGDpaper|S000077127}} PMID 14993234</ref><ref name='S000074263'>Caviston JP, et al. (2003) The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast. Mol Biol Cell 14(10):4051-66 {{SGDpaper|S000074263}} PMID 14517318</ref><ref name='S000129348'>Bartholomew CR and Hardy CF (2009) The p21-Activated Kinases Cla4 and Ste20 Regulate Vacuole Inheritance in S. cerevisiae. Eukaryot Cell
  {{SGDpaper|S000074263}} PMID 14517318</ref>
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  {{SGDpaper|S000129348}} PMID 19218422</ref>
 
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Revision as of 14:05, 2 April 2009

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Systematic name YNL298W
Gene name CLA4
Aliases ERC10
Feature type ORF, Verified
Coordinates Chr XIV:68915..71443
Primary SGDID S000005242


Description of YNL298W: Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, which also includes Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, and cytokinesis; phosphorylates septins Cdc3p and Cdc10p[1][2][3][4][5]




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References

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  1. Benton BK, et al. (1997) Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis. Mol Cell Biol 17(9):5067-76 SGD PMID 9271384
  2. Cvrckova F, et al. (1995) Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. Genes Dev 9(15):1817-30 SGD PMID 7649470
  3. Versele M and Thorner J (2004) Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J Cell Biol 164(5):701-15 SGD PMID 14993234
  4. Caviston JP, et al. (2003) The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast. Mol Biol Cell 14(10):4051-66 SGD PMID 14517318
  5. Bartholomew CR and Hardy CF (2009) The p21-Activated Kinases Cla4 and Ste20 Regulate Vacuole Inheritance in S. cerevisiae. Eukaryot Cell SGD PMID 19218422

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