Difference between revisions of "YLR409C"
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| − | '''Description of YLR409C:''' Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; synthetic defect with STI1 Hsp90 cochaperone; human homolog linked to glaucoma<ref name=' | + | '''Description of YLR409C:''' Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; synthetic defect with STI1 Hsp90 cochaperone; human homolog linked to glaucoma<ref name='S000079989'>Bernstein KA, et al. (2004) The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell 3(6):1619-26 {{SGDpaper|S000079989}} PMID 15590835</ref><ref name='S000081530'>Flom G, et al. (2005) Novel interaction of the Hsp90 chaperone machine with Ssl2, an essential DNA helicase in Saccharomyces cerevisiae. Curr Genet 47(6):368-80 {{SGDpaper|S000081530}} PMID 15871019</ref><ref name='S000086600'>Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 {{SGDpaper|S000086600}} PMID 12150911</ref><ref name='S000122805'>Perez-Fernandez J, et al. (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29 {{SGDpaper|S000122805}} PMID 17515605</ref><ref name='S000126459'>Skarie JM and Link BA (2008) The primary open-angle glaucoma gene WDR36 functions in ribosomal RNA processing and interacts with the p53 stress-response pathway. Hum Mol Genet 17(16):2474-85 |
| − | {{SGDpaper| | + | {{SGDpaper|S000126459}} PMID 18469340</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YLR409C |
| Gene name | UTP21 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:937231..934412 |
| Primary SGDID | S000004401 |
Description of YLR409C: Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; synthetic defect with STI1 Hsp90 cochaperone; human homolog linked to glaucoma[1][2][3][4][5]
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References
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- ↑ Bernstein KA, et al. (2004) The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell 3(6):1619-26 SGD PMID 15590835
- ↑ Flom G, et al. (2005) Novel interaction of the Hsp90 chaperone machine with Ssl2, an essential DNA helicase in Saccharomyces cerevisiae. Curr Genet 47(6):368-80 SGD PMID 15871019
- ↑ Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 SGD PMID 12150911
- ↑ Perez-Fernandez J, et al. (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29 SGD PMID 17515605
- ↑ Skarie JM and Link BA (2008) The primary open-angle glaucoma gene WDR36 functions in ribosomal RNA processing and interacts with the p53 stress-response pathway. Hum Mol Genet 17(16):2474-85 SGD PMID 18469340
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