Difference between revisions of "YGR175C"

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'''Description of YGR175C:''' Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine<ref name='S000057708'>Satoh T, et al. (1993) Enzymatic properties of squalene epoxidase from Saccharomyces cerevisiae. Biol Pharm Bull 16(4):349-52 {{SGDpaper|S000057708}} PMID 8358382</ref><ref name='S000046115'>Jandrositz A, et al. (1991) The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization. Gene 107(1):155-60
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'''Description of YGR175C:''' Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine<ref name='S000046115'>Jandrositz A, et al. (1991) The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization. Gene 107(1):155-60 {{SGDpaper|S000046115}} PMID 1743514</ref><ref name='S000057708'>Satoh T, et al. (1993) Enzymatic properties of squalene epoxidase from Saccharomyces cerevisiae. Biol Pharm Bull 16(4):349-52
  {{SGDpaper|S000046115}} PMID 1743514</ref>
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  {{SGDpaper|S000057708}} PMID 8358382</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YGR175C
Gene name ERG1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:848428..846938
Primary SGDID S000003407


Description of YGR175C: Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine[1][2]




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References

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  1. Jandrositz A, et al. (1991) The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization. Gene 107(1):155-60 SGD PMID 1743514
  2. Satoh T, et al. (1993) Enzymatic properties of squalene epoxidase from Saccharomyces cerevisiae. Biol Pharm Bull 16(4):349-52 SGD PMID 8358382

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