Difference between revisions of "YOR166C"

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'''Description of YOR166C:''' Putative protein of unknown function; predicted to contain a PINc domain (PilT N terminus)<ref name='S000117836'>Strasser K (2006)   () {{SGDpaper|S000117836}} PMID </ref><ref name='S000116956'>Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9
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'''Description of YOR166C:''' RNA endoribonuclease involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain<ref name='S000128898'>Skruzny M, et al. (2009) An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol 7(1):e8 {{SGDpaper|S000128898}} PMID 19127978</ref><ref name='S000119211'>Rother S, et al. (2006) Swt1, a novel yeast protein, functions in transcription. J Biol Chem 281(48):36518-25 {{SGDpaper|S000119211}} PMID 17030511</ref><ref name='S000116956'>Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9
 
  {{SGDpaper|S000116956}} PMID 16769905</ref>
 
  {{SGDpaper|S000116956}} PMID 16769905</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YOR166C
Gene name SWT1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:648503..647127
Primary SGDID S000005692


Description of YOR166C: RNA endoribonuclease involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain[1][2][3]




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References

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  1. Skruzny M, et al. (2009) An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol 7(1):e8 SGD PMID 19127978
  2. Rother S, et al. (2006) Swt1, a novel yeast protein, functions in transcription. J Biol Chem 281(48):36518-25 SGD PMID 17030511
  3. Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9 SGD PMID 16769905

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