YOR166C
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| Systematic name | YOR166C |
| Gene name | SWT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:648502..647126 |
| Primary SGDID | S000005692 |
Description of YOR166C: RNA endoribonuclease involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain[1][2][3]
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References
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- ↑ Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9 SGD PMID 16769905
- ↑ Rother S, et al. (2006) Swt1, a novel yeast protein, functions in transcription. J Biol Chem 281(48):36518-25 SGD PMID 17030511
- ↑ Skruzny M, et al. (2009) An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol 7(1):e8 SGD PMID 19127978
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