Difference between revisions of "YOL077C"

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'''Description of YOL077C:''' Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif<ref name='S000076470'>Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 {{SGDpaper|S000076470}} PMID 15100437</ref><ref name='S000069545'>Wehner KA and Baserga SJ (2002) The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell 9(2):329-39 {{SGDpaper|S000069545}} PMID 11864606</ref><ref name='S000069148'>Kaser A, et al. (2001) Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits. Biol Chem 382(12):1637-47 {{SGDpaper|S000069148}} PMID 11843177</ref><ref name='S000068847'>Bogengruber E, et al. (2003) Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes. FEMS Yeast Res 3(1):35-43
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'''Description of YOL077C:''' Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif<ref name='S000076470'>Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 {{SGDpaper|S000076470}} PMID 15100437</ref><ref name='S000068847'>Bogengruber E, et al. (2003) Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes. FEMS Yeast Res 3(1):35-43 {{SGDpaper|S000068847}} PMID 12702244</ref><ref name='S000069545'>Wehner KA and Baserga SJ (2002) The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell 9(2):329-39 {{SGDpaper|S000069545}} PMID 11864606</ref><ref name='S000069148'>Kaser A, et al. (2001) Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits. Biol Chem 382(12):1637-47
{{SGDpaper|S000068847}} PMID 12702244</ref>
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{{SGDpaper|S000069148}} PMID 11843177</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YOL077C
Gene name BRX1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:186723..185848
Primary SGDID S000005437


Description of YOL077C: Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif[1][2][3][4]




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References

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  1. Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 SGD PMID 15100437
  2. Bogengruber E, et al. (2003) Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes. FEMS Yeast Res 3(1):35-43 SGD PMID 12702244
  3. Wehner KA and Baserga SJ (2002) The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell 9(2):329-39 SGD PMID 11864606
  4. Kaser A, et al. (2001) Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits. Biol Chem 382(12):1637-47 SGD PMID 11843177

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