YOL077C
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| Systematic name | YOL077C |
| Gene name | BRX1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:186723..185848 |
| Primary SGDID | S000005437 |
Description of YOL077C: Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif[1][2][3][4]
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References
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- ↑ Bogengruber E, et al. (2003) Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes. FEMS Yeast Res 3(1):35-43 SGD PMID 12702244
- ↑ Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 SGD PMID 15100437
- ↑ Kaser A, et al. (2001) Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits. Biol Chem 382(12):1637-47 SGD PMID 11843177
- ↑ Wehner KA and Baserga SJ (2002) The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell 9(2):329-39 SGD PMID 11864606
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