Difference between revisions of "YML069W"
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| − | '''Description of YML069W:''' Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA | + | '''Description of YML069W:''' Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Pol II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure; interacts with DNA polymerase alpha (Pol1p)<ref name='S000052704'>Wittmeyer J and Formosa T (1997) The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein. Mol Cell Biol 17(7):4178-90 {{SGDpaper|S000052704}} PMID 9199353</ref><ref name='S000048981'>Brewster NK, et al. (1998) Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression. J Biol Chem 273(34):21972-9 {{SGDpaper|S000048981}} PMID 9705338</ref><ref name='S000043153'>Evans DR, et al. (1998) The yeast protein complex containing cdc68 and pob3 mediates core-promoter repression through the cdc68 N-terminal domain. Genetics 150(4):1393-405 |
{{SGDpaper|S000043153}} PMID 9832518</ref> | {{SGDpaper|S000043153}} PMID 9832518</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YML069W |
| Gene name | POB3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:135500..137158 |
| Primary SGDID | S000004534 |
Description of YML069W: Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Pol II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure; interacts with DNA polymerase alpha (Pol1p)[1][2][3]
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References
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- ↑ Wittmeyer J and Formosa T (1997) The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein. Mol Cell Biol 17(7):4178-90 SGD PMID 9199353
- ↑ Brewster NK, et al. (1998) Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression. J Biol Chem 273(34):21972-9 SGD PMID 9705338
- ↑ Evans DR, et al. (1998) The yeast protein complex containing cdc68 and pob3 mediates core-promoter repression through the cdc68 N-terminal domain. Genetics 150(4):1393-405 SGD PMID 9832518
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