Difference between revisions of "YGL252C"

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'''Description of YGL252C:''' Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p<ref name='S000043674'>Sekito T, et al. (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell 11(6):2103-15 {{SGDpaper|S000043674}} PMID 10848632</ref><ref name='S000044921'>Liao X and Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72(1):61-71 {{SGDpaper|S000044921}} PMID 8422683</ref><ref name='S000050990'>Komeili A, et al. (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78 {{SGDpaper|S000050990}} PMID 11076970</ref><ref name='S000074403'>Sekito T, et al. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell 13(3):795-804 {{SGDpaper|S000074403}} PMID 11907262</ref><ref name='S000074762'>Liu Z, et al. (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol Cell 12(2):401-11
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'''Description of YGL252C:''' Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p<ref name='S000074762'>Liu Z, et al. (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol Cell 12(2):401-11 {{SGDpaper|S000074762}} PMID 14536080</ref><ref name='S000074403'>Sekito T, et al. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell 13(3):795-804 {{SGDpaper|S000074403}} PMID 11907262</ref><ref name='S000050990'>Komeili A, et al. (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78 {{SGDpaper|S000050990}} PMID 11076970</ref><ref name='S000044921'>Liao X and Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72(1):61-71 {{SGDpaper|S000044921}} PMID 8422683</ref><ref name='S000043674'>Sekito T, et al. (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell 11(6):2103-15
  {{SGDpaper|S000074762}} PMID 14536080</ref>
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  {{SGDpaper|S000043674}} PMID 10848632</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YGL252C
Gene name RTG2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:27484..25718
Primary SGDID S000003221


Description of YGL252C: Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p[1][2][3][4][5]




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References

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  1. Liu Z, et al. (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol Cell 12(2):401-11 SGD PMID 14536080
  2. Sekito T, et al. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell 13(3):795-804 SGD PMID 11907262
  3. Komeili A, et al. (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78 SGD PMID 11076970
  4. Liao X and Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72(1):61-71 SGD PMID 8422683
  5. Sekito T, et al. (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell 11(6):2103-15 SGD PMID 10848632

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