YGL252C
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| Systematic name | YGL252C |
| Gene name | RTG2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:27484..25718 |
| Primary SGDID | S000003221 |
Description of YGL252C: Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p[1][2][3][4][5]
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References
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- ↑ Komeili A, et al. (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78 SGD PMID 11076970
- ↑ Liao X and Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72(1):61-71 SGD PMID 8422683
- ↑ Liu Z, et al. (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol Cell 12(2):401-11 SGD PMID 14536080
- ↑ Sekito T, et al. (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell 11(6):2103-15 SGD PMID 10848632
- ↑ Sekito T, et al. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell 13(3):795-804 SGD PMID 11907262
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