Difference between revisions of "YKL004W"
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| − | '''Description of YKL004W:''' Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance | + | '''Description of YKL004W:''' Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance<ref name='S000053853'>Nagiec MM, et al. (1997) Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J Biol Chem 272(15):9809-17 {{SGDpaper|S000053853}} PMID 9092515</ref><ref name='S000054617'>Heidler SA and Radding JA (1995) The AUR1 gene in Saccharomyces cerevisiae encodes dominant resistance to the antifungal agent aureobasidin A (LY295337). Antimicrob Agents Chemother 39(12):2765-9 |
| − | {{SGDpaper| | + | {{SGDpaper|S000054617}} PMID 8593016</ref> |
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Revision as of 04:40, 18 December 2008
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| Systematic name | YKL004W |
| Gene name | AUR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:435223..436428 |
| Primary SGDID | S000001487 |
Description of YKL004W: Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance[1][2]
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References
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- ↑ Nagiec MM, et al. (1997) Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J Biol Chem 272(15):9809-17 SGD PMID 9092515
- ↑ Heidler SA and Radding JA (1995) The AUR1 gene in Saccharomyces cerevisiae encodes dominant resistance to the antifungal agent aureobasidin A (LY295337). Antimicrob Agents Chemother 39(12):2765-9 SGD PMID 8593016
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