YPR061C

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Systematic name YPR061C
Gene name JID1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:676882..675977
Primary SGDID S000006265


Description of YPR061C: Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae[1][2]




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References

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  1. Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 SGD PMID 14671320
  2. Taxis C, et al. (2003) Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD. J Biol Chem 278(38):35903-13 SGD PMID 12847107

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