YPR057W
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| Systematic name | YPR057W |
| Gene name | BRR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:672471..673496 |
| Primary SGDID | S000006261 |
Description of YPR057W: snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed[1][2][3]
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References
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- ↑ Liu Q, et al. (1997) The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell 90(6):1013-21 SGD PMID 9323129
- ↑ Noble SM and Guthrie C (1996) Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations. Genetics 143(1):67-80 SGD PMID 8722763
- ↑ Noble SM and Guthrie C (1996) Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs. EMBO J 15(16):4368-79 SGD PMID 8861964
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