YPR054W

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Systematic name YPR054W
Gene name SMK1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:666280..667446
Primary SGDID S000006258


Description of YPR054W: Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p[1][2][3][4]




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References

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  1. Huang LS, et al. (2005) The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 102(35):12431-6 SGD PMID 16116083
  2. Krisak L, et al. (1994) SMK1, a developmentally regulated MAP kinase, is required for spore wall assembly in Saccharomyces cerevisiae. Genes Dev 8(18):2151-61 SGD PMID 7958885
  3. Pierce M, et al. (1998) Transcriptional regulation of the SMK1 mitogen-activated protein kinase gene during meiotic development in Saccharomyces cerevisiae. Mol Cell Biol 18(10):5970-80 SGD PMID 9742114
  4. Wagner M, et al. (1999) Distinct steps in yeast spore morphogenesis require distinct SMK1 MAP kinase thresholds. Genetics 151(4):1327-40 SGD PMID 10101160

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