YPR024W
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| Systematic name | YPR024W |
| Gene name | YME1 |
| Aliases | OSD1, YTA11 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:610481..612724 |
| Primary SGDID | S000006228 |
Description of YPR024W: Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; also has a role in intermembrane space protein folding; mutation causes an elevated rate of mitochondrial turnover[1][2][3][4][5]
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References
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- ↑ Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 SGD PMID 9683639
- ↑ Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
- ↑ Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 SGD PMID 10192337
- ↑ Schreiner B, et al. (2012) Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria. Mol Biol Cell () SGD PMID 22993211
- ↑ Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 SGD PMID 8514129
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