YPL239W
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| Systematic name | YPL239W |
| Gene name | YAR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:99484..100086 |
| Primary SGDID | S000006160 |
Description of YPL239W: Nucleocytoplasmic shuttling chaperone specific for Rps3p; binds Rps3p, a small ribosomal rpotein, to prevent subunit aggregation prior to assembly in the 40s ribosome; proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock[1][2][3][4]
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References
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- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Koch B, et al. (2012) Yar1 protects the ribosomal protein Rps3 from aggregation. J Biol Chem 287(26):21806-15 SGD PMID 22570489
- ↑ Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 SGD PMID 15611164
- ↑ Lycan DE, et al. (1996) A new Saccharomyces cerevisiae ankyrin repeat-encoding gene required for a normal rate of cell proliferation. Gene 171(1):33-40 SGD PMID 8675027
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