YPL190C
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| Systematic name | YPL190C |
| Gene name | NAB3 |
| Aliases | HMD1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:187725..185317 |
| Primary SGDID | S000006111 |
Description of YPL190C: RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with the exosome to mediate 3′ end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing[1][2][3][4]
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References
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- ↑ Carroll KL, et al. (2004) Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts. Mol Cell Biol 24(14):6241-52 SGD PMID 15226427
- ↑ Conrad NK, et al. (2000) A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics 154(2):557-71 SGD PMID 10655211
- ↑ Steinmetz EJ, et al. (2001) RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts. Nature 413(6853):327-31 SGD PMID 11565036
- ↑ Wilson SM, et al. (1994) Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol 127(5):1173-84 SGD PMID 7962083
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