YPL183C
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Systematic name | YPL183C |
Gene name | RTT10 |
Aliases | ERE2, TRM734 |
Feature type | ORF, Verified |
Coordinates | Chr XVI:202536..199495 |
Primary SGDID | S000006104 |
Description of YPL183C: WD40 domain-containing protein involved in endosomal recycling; forms a complex with Rrt2p that functions in the retromer-mediated pathway for recycling internalized cell-surface proteins; evidence it interacts with Trm7p for 2'-O-methylation of N34 of substrate tRNAs; has a role in regulation of Ty1 transposition; human ortholog is WDR6[1][2][3][4]
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References
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- ↑ Guy MP, et al. (2012) Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop. RNA () SGD PMID 22912484
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 SGD PMID 18202368
- ↑ Shi Y, et al. (2011) Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway. Mol Biol Cell () SGD PMID 21880895
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