YPL164C
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| Systematic name | YPL164C |
| Gene name | MLH3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:241497..239350 |
| Primary SGDID | S000006085 |
Description of YPL164C: Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability[1][2][3][4]
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References
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- ↑ Flores-Rozas H and Kolodner RD (1998) The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A 95(21):12404-9 SGD PMID 9770499
- ↑ Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8 SGD PMID 10679328
- ↑ Lipkin SM, et al. (2000) MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability. Nat Genet 24(1):27-35 SGD PMID 10615123
- ↑ Wang TF, et al. (1999) Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A 96(24):13914-9 SGD PMID 10570173
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