YPL139C
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| Systematic name | YPL139C |
| Gene name | UME1 |
| Aliases | WTM3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:291051..289669 |
| Primary SGDID | S000006060 |
Description of YPL139C: Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p[1][2][3][4]
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References
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- ↑ Kurdistani SK, et al. (2002) Genome-wide binding map of the histone deacetylase Rpd3 in yeast. Nat Genet 31(3):248-54 SGD PMID 12089521
- ↑ Mallory MJ and Strich R (2003) Ume1p represses meiotic gene transcription in Saccharomyces cerevisiae through interaction with the histone deacetylase Rpd3p. J Biol Chem 278(45):44727-34 SGD PMID 12954623
- ↑ Pemberton LF and Blobel G (1997) Characterization of the Wtm proteins, a novel family of Saccharomyces cerevisiae transcriptional modulators with roles in meiotic regulation and silencing. Mol Cell Biol 17(8):4830-41 SGD PMID 9234739
- ↑ Strich R, et al. (1989) Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast. Proc Natl Acad Sci U S A 86(24):10018-22 SGD PMID 2690066
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