YPL135W
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| Systematic name | YPL135W |
| Gene name | ISU1 |
| Aliases | NUA1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:297553..298050 |
| Primary SGDID | S000006056 |
Description of YPL135W: Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable[1][2][3][4]
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References
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- Jump up ↑ Garland SA, et al. (1999) Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly. J Mol Biol 294(4):897-907 SGD PMID 10588895
- Jump up ↑ Muhlenhoff U, et al. (2003) Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p. EMBO J 22(18):4815-25 SGD PMID 12970193
- Jump up ↑ Ramazzotti A, et al. (2004) Mitochondrial functional interactions between frataxin and Isu1p, the iron-sulfur cluster scaffold protein, in Saccharomyces cerevisiae. FEBS Lett 557(1-3):215-20 SGD PMID 14741370
- Jump up ↑ Schilke B, et al. (1999) Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(18):10206-11 SGD PMID 10468587
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