YPL098C

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Systematic name YPL098C
Gene name MGR2
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:364727..364386
Primary SGDID S000006019


Description of YPL098C: Subunit of the TIM23 translocase complex; acts to couple Tim21p with the core Tim23 translocase; absolutely required for mitochondrial import of presequence-containing proteins at elevated temperature; required for viability of cells lacking the mitochondrial genome (petite-negative phenotype)[1][2]




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References

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  1. Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
  2. Gebert M, et al. (2012) Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol 197(5):595-604 SGD PMID 22613836

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