YPL091W

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Systematic name YPL091W
Gene name GLR1
Aliases LPG17
Feature type ORF, Verified
Coordinates Chr XVI:375502..376953
Primary SGDID S000006012


Description of YPL091W: Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione; mitochondrial but not cytosolic form has a role in resistance to hyperoxia[1][2][3]




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References

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  1. Jump up Grant CM (2001) Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions. Mol Microbiol 39(3):533-41 SGD PMID 11169096
  2. Jump up Outten CE and Culotta VC (2004) Alternative start sites in the Saccharomyces cerevisiae GLR1 gene are responsible for mitochondrial and cytosolic isoforms of glutathione reductase. J Biol Chem 279(9):7785-91 SGD PMID 14672937
  3. Jump up Outten CE, et al. (2005) Cellular factors required for protection from hyperoxia toxicity in Saccharomyces cerevisiae. Biochem J 388(Pt 1):93-101 SGD PMID 15641941

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