YPL078C

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Systematic name YPL078C
Gene name ATP4
Aliases LPF7
Feature type ORF, Verified
Coordinates Chr XVI:408744..408010
Primary SGDID S000005999


Description of YPL078C: Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; contributes to the oligomerization of the complex; phosphorylated[1][2][3][4]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [5] [6]





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References

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  1. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
  2. Soubannier V, et al. (1999) The second stalk of the yeast ATP synthase complex: identification of subunits showing cross-links with known positions of subunit 4 (subunit b). Biochemistry 38(45):15017-24 SGD PMID 10555984
  3. Velours J, et al. (1988) ATP4, the structural gene for yeast F0F1 ATPase subunit 4. Eur J Biochem 170(3):637-42 SGD PMID 2892678
  4. Weimann T, et al. (2008) The intermembrane space loop of subunit B (4) is a major determinant of the stability of yeast oligomeric ATP synthases. Biochemistry 47(11):3556-63 SGD PMID 18293929
  5. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  6. submitted by Steffen Ohlmeier on 2004-04-08

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