YPL076W

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Systematic name YPL076W
Gene name GPI2
Aliases GCR4
Feature type ORF, Verified
Coordinates Chr XVI:410443..411285
Primary SGDID S000005997


Description of YPL076W: Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein[1][2]




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References

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  1. Inoue N, et al. (1996) PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2. Biochem Biophys Res Commun 226(1):193-9 SGD PMID 8806613
  2. Leidich SD, et al. (1995) Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene. J Biol Chem 270(22):13029-35 SGD PMID 7768896

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