YPL059W
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| Systematic name | YPL059W |
| Gene name | GRX5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:444579..445031 |
| Primary SGDID | S000005980 |
Description of YPL059W: Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p[1][2][3][4]
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Protein Details
Protein Localization
Protein identified in a purified mitochondrial extract. [5] [6]
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References
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- ↑ Belli G, et al. (2002) Structure-function analysis of yeast Grx5 monothiol glutaredoxin defines essential amino acids for the function of the protein. J Biol Chem 277(40):37590-6 SGD PMID 12138088
- ↑ Grant CM, et al. (2000) Differential regulation of glutaredoxin gene expression in response to stress conditions in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1490(1-2):33-42 SGD PMID 10786615
- ↑ Rodriguez-Manzaneque MT, et al. (1999) Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae. Mol Cell Biol 19(12):8180-90 SGD PMID 10567543
- ↑ Rodriguez-Manzaneque MT, et al. (2002) Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol Biol Cell 13(4):1109-21 SGD PMID 11950925
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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