YPL020C

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Systematic name YPL020C
Gene name ULP1
Aliases NIB1
Feature type ORF, Verified
Coordinates Chr XVI:514178..512313
Primary SGDID S000005941


Description of YPL020C: Protease that specifically cleaves Smt3p protein conjugates; required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase; sequestered to the nucleolus under stress conditions[1][2][3][4]




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References

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  1. Hochstrasser M (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8 SGD PMID 11595179
  2. Li SJ and Hochstrasser M (2003) The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol 160(7):1069-81 SGD PMID 12654900
  3. Soustelle C, et al. (2004) A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability. Mol Cell Biol 24(12):5130-43 SGD PMID 15169880
  4. Sydorskyy Y, et al. (2010) A Novel Mechanism for SUMO System Control: Regulated Ulp1 Nucleolar Sequestration. Mol Cell Biol 30(18):4452-62 SGD PMID 20647537

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