YPL001W
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| Systematic name | YPL001W |
| Gene name | HAT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:554605..555729 |
| Primary SGDID | S000005922 |
Description of YPL001W: Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair[1][2][3][4][5][6]
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References
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- ↑ Dutnall RN, et al. (1998) Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamily. Cell 94(4):427-38 SGD PMID 9727486
- ↑ Kelly TJ, et al. (2000) Type B histone acetyltransferase Hat1p participates in telomeric silencing. Mol Cell Biol 20(19):7051-8 SGD PMID 10982821
- ↑ Kleff S, et al. (1995) Identification of a gene encoding a yeast histone H4 acetyltransferase. J Biol Chem 270(42):24674-7 SGD PMID 7559580
- ↑ Parthun MR, et al. (1996) The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell 87(1):85-94 SGD PMID 8858151
- ↑ Qin S and Parthun MR (2002) Histone H3 and the histone acetyltransferase Hat1p contribute to DNA double-strand break repair. Mol Cell Biol 22(23):8353-65 SGD PMID 12417736
- ↑ Ruiz-Garcia AB, et al. (1998) HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4. J Biol Chem 273(20):12599-605 SGD PMID 9575221
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